Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis
Selected by
Julio Molina Pineda
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4
Selected by
Aniruddha Das
VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity
Selected by
Kritika Mehta
Motion of single molecular tethers reveals dynamic subdomains at ER-mitochondria contact sites
Selected by
Holly Smith
A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis
Selected by
Utrecht Protein Folding and Assembly
Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates
Selected by
Kristina Kuhbandner
FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Selected by
Sree Rama Chaitanya, Giuseppina D'Alessandro
Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
Selected by
Kristina Kuhbandner
amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex
Selected by
Kristina Kuhbandner
FUS gene is dual-coding with both proteins united in FUS-mediated toxicity
Selected by
Madhuja Samaddar
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
Selected by
Madhuja Samaddar
Generalized displacement of DNA- and RNA-binding factors mediates the toxicity of arginine-rich cell-penetrating peptides
Selected by
Emily Graves